What Is NAD+ IV Therapy?
NAD+ IV therapy delivers nicotinamide adenine dinucleotide directly into the bloodstream, bypassing the digestive system for 100% bioavailability. The infusion rapidly raises cellular NAD+ levels — a process that takes weeks via oral supplementation. Clinics offering NAD+ IV have proliferated in the UK, particularly in London, since 2020.
What Does the Evidence Say?
IV NAD+ does raise blood and cellular NAD+ levels — that’s well-established. What’s less clear is whether the short-term spike from a single infusion translates into meaningful longevity or health benefits beyond what consistent oral NMN/NR supplementation provides. There are no long-term RCTs in healthy aging adults. Most positive reports are anecdotal or from addiction/withdrawal clinics where NAD+ IV has a different (and somewhat better-evidenced) application.
What to Expect From a Session
A typical session lasts 2–4 hours. Common side effects during infusion include chest tightness, nausea, flushing and rapid heart rate — largely manageable by slowing the infusion rate. After infusion, many patients report improved energy and mental clarity, though placebo effects in this context are notoriously difficult to separate from biological effects.
Costs and Clinics
UK NAD+ IV therapy costs £300–800 per infusion. London clinics include Reviv, IV Boost, and several aesthetic/wellness practices. Monthly maintenance protocols can cost £1,000–3,000/year. Whether this justifies the spend over £50/month of oral NAD+ precursors is a question worth asking seriously.
⚕️ IV therapy carries risks including infection, embolism and adverse reactions. Only attend CQC-registered or medically supervised clinics. Always consult your GP first.