This is your definitive guide to longevity science — covering everything from the biology of ageing to practical interventions you can start today. We’ve compiled our best research into one comprehensive resource, with links to our in-depth articles on each topic.
Last Updated: 21 March 2026
Understanding the Science of Ageing
Ageing isn’t just about getting older — it’s a complex biological process driven by specific mechanisms that scientists are increasingly learning to influence. The nine hallmarks of ageing include genomic instability, telomere attrition, epigenetic alterations, and cellular senescence, among others.
→ Read more: Telomere Testing UK: Where to Get Tested and What It Means
→ Read more: Resveratrol Dosage for Anti-Aging: What Research Shows
Anti-Ageing Interventions That Actually Work
Not every supplement or therapy lives up to its claims. Here are the interventions with the strongest evidence:
NAD+ and NMN Supplementation
NAD+ levels decline with age, and supplementing with NMN or NR precursors has shown promise in animal studies and early human trials. Our guides cover dosing, brands, and realistic expectations.
→ NAD+ Supplements vs IV Therapy: Which Works Better?
Rapamycin and mTOR Inhibition
Originally an immunosuppressant, rapamycin has emerged as one of the most promising longevity compounds in research.
→ Rapamycin for Longevity: Dosage and Side Effects — An Expert Review
Metformin for Longevity
The TAME trial is investigating metformin’s potential to slow ageing in humans. Here’s what we know so far.
→ Metformin Anti-Ageing: Benefits and Risks — An Evidence-Based Overview
Peptide Therapy
Peptides like BPC-157, TB-500, and CJC-1295 are gaining attention for their potential therapeutic benefits. Our guides cover the science, legal status in the UK, and practical considerations.
→ Best Peptide Therapy Providers UK: 2026 Review
Biohacking and Health Optimisation
From cold exposure and red light therapy to hyperbaric oxygen and continuous glucose monitoring — these are the biohacking tools with evidence behind them.
→ Hyperbaric Oxygen Therapy for Anti-Aging: UK Clinics
→ Best Wearables for Tracking Longevity Biomarkers 2026
Nutrition for Longevity
The Mediterranean diet, caloric restriction, time-restricted eating — what does the research actually say about diet and lifespan?
→ Caloric Restriction Mimetics Supplements Guide 2026
Sleep and Recovery
Sleep is arguably the most underrated longevity intervention. Poor sleep accelerates biological ageing and increases disease risk.
→ How Sleep Quality Directly Impacts Your Lifespan
Testing and Monitoring Your Biological Age
You can’t improve what you don’t measure. These are the best biomarker tests and longevity assessments available in the UK.
→ Best Longevity Blood Tests to Track Biological Age UK
→ Best Longevity Clinics in the UK: 2026 Expert Review
Frequently Asked Questions
What is the most effective longevity intervention?
The evidence points to a combination of lifestyle factors — regular exercise, quality sleep, a nutrient-dense diet, and stress management — as the most effective overall approach. Among pharmaceutical interventions, rapamycin and metformin show the most promise based on current research.
Can you really slow down ageing?
Yes — at least in terms of biological age. Emerging research shows that targeted interventions can measurably reduce your biological age as assessed by epigenetic clocks and other biomarkers, even if chronological age continues to advance.
How much do longevity programs cost in the UK?
UK longevity programmes range from a few hundred pounds for basic testing and supplementation plans, to several thousand per year for comprehensive clinical programmes. See our honest review of 5 UK longevity programmes for a cost breakdown.
What supplements have the best evidence for anti-ageing?
The supplements with the strongest evidence include NMN/NR (NAD+ precursors), resveratrol, spermidine, fisetin, and quercetin. Each has a different mechanism of action and evidence base — our individual guides cover each in detail.
Keep Learning
Bookmark this page — we update it regularly as new research emerges.